2020年 筑波大学内分泌代謝・糖尿病内科の研究業績を掲載しています。

Nakagawa Y, Wang Y, Han SI, Okuda K, Oishi A, Yagishita Y, Kumagai K, Ohno H, Osaki Y, Mizunoe Y, Araki M, Murayama Y, Iwasaki H, Konishi M, Itoh N, Matsuzaka T, Sone H, Yamada N, Shimano H.

Enterohepatic Transcription Factor CREB3L3 Protects Atherosclerosis via SREBP Competitive Inhibition. Cell Mol Gastroenterol Hepatol. 2021;11(4):949-971. doi: 10.1016/j.jcmgh.2020.11.004. Epub 2020 Nov 24. PMID: 33246135; PMCID: PMC7900604.

Sekiya M, Matsuda T, Yamamoto Y, Furuta Y, Ohyama M, Murayama Y, Sugano Y, Ohsaki Y, Iwasaki H, Yahagi N, Yatoh S, Suzuki H, Shimano H.

Deciphering genetic signatures by whole exome sequencing in a case of co-prevalence of severe renal hypouricemia and diabetes with impaired insulin secretion. BMC Med Genet. 2020 May 6;21(1):91. doi: 10.1186/s12881-020-01031-z. PMID: 32375679; PMCID: PMC7201978.

Matsuzaka T, Shimano H.

New perspective on type 2 diabetes, dyslipidemia and non-alcoholic fatty liver disease. J Diabetes Investig. 2020 May;11(3):532-534. doi: 10.1111/jdi.13258. Epub 2020 May 12. PMID: 32232972; PMCID: PMC7232277.

Satoh A, Han SI, Araki M, Nakagawa Y, Ohno H, Mizunoe Y, Kumagai K, Murayama Y, Osaki Y, Iwasaki H, Sekiya M, Konishi M, Itoh N, Matsuzaka T, Sone H, Shimano H.

CREBH Improves Diet-Induced Obesity, Insulin Resistance, and Metabolic Disturbances by FGF21-Dependent and FGF21-Independent Mechanisms. iScience. 2020 Mar 27;23(3):100930. doi: 10.1016/j.isci.2020.100930. Epub 2020 Feb 21. PMID: 32151974; PMCID: PMC7063134.

Ma Y, Sekiya M, Kainoh K, Matsuda T, Iwasaki H, Osaki Y, Sugano Y, Suzuki H, Takeuchi Y, Miyamoto T, Yahagi N, Nakagawa Y, Matsuzaka T, Shimano H.

Transcriptional co-repressor CtBP2 orchestrates epithelial-mesenchymal transition through a novel transcriptional holocomplex with OCT1. Biochem Biophys Res Commun. 2020 Mar 5;523(2):354-360. doi: 10.1016/j.bbrc.2019.12.070. Epub 2019 Dec 19. PMID: 31866012.

Matsuzaka T, Kuba M, Koyasu S, Yamamoto Y, Motomura K, Arulmozhiraja S, Ohno H, Sharma R, Shimura T, Okajima Y, Han SI, Aita Y, Mizunoe Y, Osaki Y, Iwasaki H, Yatoh S, Suzuki H, Sone H, Takeuchi Y, Yahagi N, Miyamoto T, Sekiya M, Nakagawa Y, Ema M, Takahashi S, Tokiwa H, Shimano H.

Hepatocyte ELOVL Fatty Acid Elongase 6 Determines Ceramide Acyl-Chain Length and Hepatic Insulin Sensitivity in Mice. Hepatology. 2020 May;71(5):1609-1625. doi: 10.1002/hep.30953. Epub 2020 Feb 7. PMID: 31529722.